wilderness wil·der·ness \ˈwil-dər-nəs\ 1a (1) : a tract or region uncultivated and uninhabited by human beings (2) : an area essentially undisturbed by human activity together with its naturally developed life communityb : an empty or pathless area or regionc : a part of a garden devoted to wild growth 2 obsolete : wild or uncultivated state 3a : a confusing multitude or mass : an indefinitely great number or quantity b : a bewildering situation